Methods for modulating cell growth, and for treating and / or prophylaxis a condition distinguished by aberrant, undesirable or otherwise inappropriate cell growth in a mammal, use of an agent capable of modulating the functional activity of sphingosine kinase , pharmaceutical composition, and method of diagnosing a condition, or a predisposition or resistance to a condition, distinguished by aberrant, undesirable, or otherwise inappropriate cell growth in a mammal

摘要

"METHODS FOR MODULATING THE GROWTH OF A CELL, AND FOR THE TREATMENT AND / OR PROPHILAXIS OF A CONDITION DISTINGUISHED BY UNDESIRABLE ABSTRACT CELLULAR OR OTHERWISE NOT APPROPRIATE IN A MAMMIFEROUS USE OF A FACULATION OF A FACULAR CASSATIVE AGING" PHARMACEUTICAL COMPOSITION, AND METHOD OF DIAGNOSIS OF A CONDITION, OR A PREDISPOSITION OR RESISTANCE TO A CONDITION, DISTINGUISHED BY ABSTRACT, UNDESIRABLE, OR OTHERWISE NOT APPROPRIATE CELLULAR GROWTH. The present invention relates generally to a method of modulating cell growth and, more particularly, to a method for down-regulating neoplastic cell growth. The present invention is useful, inter alia, in the therapeutic and / or prophylactic treatment of cancers such that, but not limited to, solid cancers, such as cancers of the colon, stomach, lung, brain, bone, esophagus, pancreas, breast, ovary and uterus.