首页> 外国专利> Tartrate Salt of 5,8,14 - triazatetraciclo - 10.3.1.0 2.11.Hexadeca 0 4.9 - 2 - (11) - pentaeno polymorphs, 3,5,7,9; a, B and C; Pharmaceutical compositions, and use in the treatment of inflammatory bowel disease, depression, anxiety,Parkinson's disease, Epilepsy and nicotine dependence and Addiction.

Tartrate Salt of 5,8,14 - triazatetraciclo - 10.3.1.0 2.11.Hexadeca 0 4.9 - 2 - (11) - pentaeno polymorphs, 3,5,7,9; a, B and C; Pharmaceutical compositions, and use in the treatment of inflammatory bowel disease, depression, anxiety,Parkinson's disease, Epilepsy and nicotine dependence and Addiction.

机译:5,8,14的酒石酸盐-三氮杂环烷-[10.3.1.0 2.11.Hexadeca 0 4.9]-2-(11)-五烯多晶型,3,5,7,9; a,B和C;药物组合物,并用于治疗炎性肠病,抑郁症,焦虑症,帕金森氏病,癫痫和尼古丁依赖性和成瘾性。

摘要

Trartrato salts of 5,8,14 - triazatetraciclo (10.3.1.02,11.0.Hexadeca 4.9) - 2 - (11) - pentaeno: 3,5,7,9 and Pharmaceutical compositions that contain.In particular, The Invention relates to the L - Tartrate Salt and in addition to the various polymorphs of Salt.Tartrate, anhydrous polymorphs, including two different (called in this paper forms a Polymorph a and b) and hydrated (referred to in this document is (c).In addition, the present Invention also relates to the Salt of 5,8,14 - traizatetraciclo d-tartrate (10.3.1.0.2,11.04,9 hexadeca) - 2 - (11) - 3,5,7,9 pentaeno and the various polymorphs of the same; as well as the salt (D, L - Tartrate and its polymorphs of this Compound.And the meso Tartrate Salt of the compound and its polymorphs. Includes their use in modulating cholinergic function to treat inflammatory bowel disease.
机译:5,8,14-三氮杂双环(10.3.1.02,11.0。十六烷4.9)-2-(11)-五烯酮的特拉特罗盐:3,5,7,9及其所含的药物组合物。 L-酒石酸盐和除盐的各种多晶型物。酒石酸盐外,无水多晶型物包括两种不同的(本文称其为多晶型物a和b)并被水合(在本文件中称为(c)。本发明还涉及5,8,14-曲沙四环酒石酸酒石酸盐(10.3.1.0.2,11.04,9十六烷基)-2-(11)-3,5,7,9五烯酮的盐和各种多晶型物;以及该化合物的盐(D,L-酒石酸盐及其多晶型物。以及该化合物及其多晶型的内消旋酒石酸盐。包括其在调节胆碱能功能方面的用途,以治疗炎症性肠病。

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