首页> 外国专利> Use of compounds derived from Carbamoyl esters, carbamates, esters, acid sulfamico,As dual inhibitors of the synthesis of esters and Cholesteryl Esters cereos to inhibit sebum Production.

Use of compounds derived from Carbamoyl esters, carbamates, esters, acid sulfamico,As dual inhibitors of the synthesis of esters and Cholesteryl Esters cereos to inhibit sebum Production.

机译:衍生自氨基甲酸酯,氨基甲酸酯,酯,酸性磺胺类的化合物作为酯和胆固醇酯的合成的双重抑制剂,可抑制皮脂的产生。

摘要

The Invention relates to a method for inhibiting sebum production and to treat disorders of the sebaceous glands.Which comprises administering to a patient in need of such treatment an effective amount of a compound that Inhibits both the Acyl coenzina: cholesterol acyltransferase (ACAT) as the Acyl coenzinaTo: alcohol - aciltrasferasa (afat), under the condition that the compound is not the Ester - 2.6 - disopropyl phenyl acid ((2.4,6 - triisopropil - phenyl) - acetyl - sulfamico) or one of its Salts or solvates farmaceuticamnte acceptable.The Method of the invention is useful for treating sebaceous Gland Disorders caused or exacerbated by the overproduction of sebum.Including Oily Skin, acne, seborrhea, perioral dermatitis, rosasea, and aceniformes lesions induced by corticosteroids.
机译:本发明涉及一种抑制皮脂产生和治疗皮脂腺疾病的方法。该方法包括向需要这种治疗的患者施用有效量的同时抑制酰基辅酶:胆固醇酰基转移酶(ACAT)的化合物。酰基coenzinaTo:酒精-aciltrasferasa(afat),条件是该化合物不是酯-2.6-二异丙基苯基酸((2.4,6--三异丙醇-苯基)-乙酰基-磺胺类)或其盐或溶剂化物之一本发明的方法可用于治疗由皮脂过度产生引起或加剧的皮脂腺疾病,包括油性皮肤,痤疮,皮脂溢,口周皮炎,酒渣鼻和由皮质类固醇引起的痤疮。

著录项

  • 公开/公告号CL2002001684A1

    专利类型

  • 公开/公告日2003-07-04

    原文格式PDF

  • 申请/专利权人 WARNER-LAMBERT COMPANY;

    申请/专利号CL2002001684

  • 发明设计人 HOMAN REYNOLD;

    申请日2002-07-30

  • 分类号

  • 国家 CL

  • 入库时间 2022-08-22 00:03:35

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