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Protease inhibitors of the HIV virus, formulations containing the same, their pharmaceutical applications and Ingredients for their Synthesis.

机译:HIV病毒的蛋白酶抑制剂,含有该蛋白酶的制剂,其药物应用和合成成分。

摘要

Compounds of formula (I) where the formula variables are as defined herein, are disclosed that advantageously inhibit or block the biological activity of the HIV protease. Theses compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with the HIV virus. Intermediates and synthetic methods for preparing such compounds are also described. I
机译:公开了其中式变量如本文所定义的式(I)化合物,其有利地抑制或阻断HIV蛋白酶的生物学活性。这些化合物以及包含这些化合物的药物组合物可用于治疗感染了HIV病毒的患者或宿主。还描述了制备此类化合物的中间体和合成方法。一世

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