USE OF INDOLOQUINOXALINE DERIVATIVES FOR PREPARING A DRUG FOR TREATMENT OF MS

摘要

The present invention relates to the use of a substituted indole quinoxaline derivative of formula (I) and its addition products with physiologically acceptable acid halide adducts, preferably iodides, iodine monochlorides or iodine monobromides, for the preparation of a medicament for the treatment of multiple sclerosis. or a plurality of, preferably 1-4, identical or different substituents at the 1-4 and / or 7-10 positions selected from the group consisting of halogen, preferably bromine, alkyl and / or alkoxy having up to 4 carbon atoms, trifluoromethyl, trichloromethyl or, when R1 is attached to one of positions 7 to 10, it may also represent a hydroxy group; X is - (CH 2) n -R 2, wherein R 2 is a basic nitrogen-containing group such as -NH 2, -NHR 4, or -NR 5 R 6 where R 4, R 5 and R 6 are independently lower alkyl or cycloalkyl; An integer from 1 to 4; R3 is hydrogen, alkyl or cycloalkyl having up to 4 carbon atoms. HE