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21-HYDROXY-6, 19-OXIDOPROGESTERONE (21OH-6, 19OP) ANALOGUES, THEIR PREPARATION AND USE
21-HYDROXY-6, 19-OXIDOPROGESTERONE (21OH-6, 19OP) ANALOGUES, THEIR PREPARATION AND USE
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机译:21-羟基-6、19-氧孕酮(21OH-6、19OP)类似物,其制备和使用
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摘要
The present invention is related to novel 21-hydroxy-6,19-oxidoprogesterone (21OH-6OP) analogues, their use as antiglucocorticoids for the treatment and/or prophylaxis of disease associated to an excess of glucocorticoids. In particular, the invention relates to the use of novel 21-hydroxy-6,19-oxidoprogesterone (21OH-6OP) analogues for treating Cushing's syndrome, iatrogenic hypercortisolism or depression. Also the present invention is related to methods of preparing the novel 21-hydroxy-6,19-oxidoprogesterone (21OH-6OP) analogues.
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