MEDICAMENT FOR THE STIMULATION OF LEUCOPOIESIS AND TREATMENT OF TUMOUR AND PROTOZOAN DISEASES ACARINOSIS AND ARTHROPOD BORNE DISEASES AND A METHOD FOR PRODUCTION THEREOF.

摘要

The invention relates to drug formulations for stimulating leukopoiesis and for treating tumor diseases and protozoal diseases, and acariasis and diseases caused by arthropods, which formulations are characterized in that they comprise an effective mixture composed of a) at least one phospholipid compound of the formula I: in which R1 is a saturated or unsaturated hydrocarbon radical having from 16 to 24 C atoms, R2, R3 and R4 are, in each case independently, H, a C1-C5-alkyl group, a C3-C6-cycloalkyl group or a C1-C5-hydroxyalkyl group, with two of R2, R3 and R4 being able to form, with each other, a C2-C5-alkylene group which can optionally be substituted by an -O-, -S- or NR5 group, in which R5 is H, a C1-C5-alkyl group, a C3-C6-cycloalkyl group or a C1-C5-hydroxyalkyl group, and n is an integer from 2 to 6, as the active compound, comprising from 30 to 60 mol %, b) cholesterol and/or a cholesterol derivative, comprising from 25 to 65 mol %, and c) a phosphatidylmonoglycerol or phosphatidyloligoglycerol containing at least one oleyl group, comprising from 5 to 15 mol %, with a), b) and c) together comprising 100 mol %, and d) a water-miscible, physiologically acceptable alcohol, which possesses from 2 to 4 C atoms and which optionally contains water, and also, where appropriate, customary pharmaceutical auxiliary substances, with the components being present as a complex which is dispersed in water. The invention also relates to a process for preparing them.