首页> 外国专利> Anvendelse av GAL3-reseptorantagonister ved behandling av depresjon og/eller angst samt forbindelser som er anvendelige ved slik behandling

Anvendelse av GAL3-reseptorantagonister ved behandling av depresjon og/eller angst samt forbindelser som er anvendelige ved slik behandling

机译:GAL3受体拮抗剂在治疗抑郁症和/或焦虑症中的用途以及可用于此类治疗的化合物

摘要

This invention is directed to pyrimidine and indolone derivatives which are selective antagonists for the GAL3 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and apharmaceutically acceptable carrier. This invention also provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject an amount of a compound of the invention effective to treat the subject's depression and/or anxiety. This invention also provides a method of treating depression and/or anxiety in a subject which comprises administering to the subject a composition comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of a GAL3 receptor antagonist.
机译:本发明涉及作为GAL3受体的选择性拮抗剂的嘧啶和吲哚酮衍生物。本发明提供了药物组合物,其包含治疗有效量的本发明的化合物和药学上可接受的载体。本发明还提供了通过将治疗有效量的本发明化合物与药学上可接受的载体结合而制成的药物组合物。本发明进一步提供了一种制备药物组合物的方法,该方法包括将治疗有效量的本发明化合物与药学上可接受的载体结合。本发明还提供了一种治疗患有抑郁症和/或焦虑症的受试者的方法,该方法包括向该受试者施用一定量的有效治疗该受试者的抑郁症和/或焦虑症的本发明化合物。本发明还提供了一种治疗受试者的抑郁和/或焦虑的方法,该方法包括向该受试者施用一种组合物,该组合物包含一种药学上可接受的载体和治疗有效量的GAL3受体拮抗剂。

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