首页> 外国专利> 6-sulphamoyl-3-quinolylphosponic acid compounds for treating hyperactivation of neurotransmission paths to excitatory amino acids, alzheimer's disease, huntington's disease, spinal or cerebral traumatism or epilepsy

6-sulphamoyl-3-quinolylphosponic acid compounds for treating hyperactivation of neurotransmission paths to excitatory amino acids, alzheimer's disease, huntington's disease, spinal or cerebral traumatism or epilepsy

机译:用于治疗兴奋性氨基酸,阿尔茨海默氏病,亨廷顿氏病,脊柱或脑外伤或癫痫的神经传递途径的过度活化的6-磺酰基3-喹啉基膦酸化合物

摘要

Compounds of formula (I), its isomers and addition salts thereof, wherein; X is chlorine, fluorine, or trifluoromethyl. R is hydrogen or CH2OC=OR', wherein; R' is hydrogen, alkyl or phenyl. Also described are pharmaceutical compositions of formula (I) and a pharmaceutically acceptable base for use in the treatment of pathological phenomena associated with hyperactivation of the neurotransmission paths to the excitatory amino acids.
机译:式(I)化合物,其异构体及其加成盐,其中; X是氯,氟或三氟甲基。 R为氢或CH 2 OC = OR',其中; R'是氢,烷基或苯基。还描述了式(I)的药物组合物和药学上可接受的碱,其用于治疗与向兴奋性氨基酸的神经传递途径的过度活化有关的病理现象。

著录项

  • 公开/公告号NZ510001A

    专利类型

  • 公开/公告日2002-11-26

    原文格式PDF

  • 申请/专利权人 LES LABORATOIRES SERVIER;

    申请/专利号NZ20010510001

  • 发明设计人 CORDI ALEX;DESOS PATRICE;LESTAGE PIERRE;

    申请日2001-02-16

  • 分类号C07D215/227;C07D215/18;C07F9/40;C07F9/60;

  • 国家 NZ

  • 入库时间 2022-08-22 00:01:41

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