5 - Butoxy - 5 - 2 - (1-hydroxyethyl) - 3-pyridinyl - 3 - ethyl - 2 - (2 - ethyl - 3 - azetidinil) - 2.6 - dihydro 7h pyrazolo 4,3-d pyrimidin-7-one as inhibitors of phosphodiesterases guanosine 3 ', 5' - cyclic monophosphate

摘要

Refers to 5 - Butoxy - 5 - [2 - (1-hydroxyethyl) - 3-pyridinyl] - 3 - ethyl - 2 - (2 - ethyl - 3 - azetidinil) - 2.6 - dihydro 7h pyrazolo [4,3-d] pyrimidin-7-one of formula I wherein R1 is H, co co c1-c4 alkyl, aryl,CO - heteroaryl on condition that are not obtained by Metabolism of 5 - (2 - 5 - acetyl - Butoxy - 3-pyridinyl) - 3 - (2 - ethyl - 2 - ethyl - 3 - azetidinil) - 2.6 - dihydro 7h pyrazolo [43 - d] pyrimidin-7-one compounds in the body are preferred; 5 - Butoxy - 5 - [2 - (1-hydroxyethyl) - 3-pyridinyl] - 3 - ethyl - 2 - (2 - ethyl - 3 - azetidinil) - 2.6 - dihydro 7h pyrazolo [43 - d] pyrimidin-7-one compounds are inhibitors of phosphodiesterases; of guanosine 3 ', 5' - cyclic monophosphate and may be useful for the treatment of male erectile dysfunction, Impotence,Female Sexual Dysfunction, dysfunction of clitoris, Female Hypoactive Sexual Desire Disorder, Female sexual arousal disorder,Female Sexual Pain disorder or sexual Female Orgasmic dysfunction