1-η1- (4-CHLOROPHENYL) CYCLOBUTYL-3-METHYL-BUTYLAMINE DERIVATIVES FOR REDUCING URINE ACID LEVELS IN HUMAN BEINGS

摘要

PCT No. PCT/EP97/05034 Sec. 371 Date Mar. 25, 1999 Sec. 102(e) Date Mar. 25, 1999 PCT Filed Sep. 15, 1997 PCT Pub. No. WO98/13033 PCT Pub. Date Apr. 2, 1998A compound of formula I or a pharmaceutically acceptable salt thereof in which R1 and R2 are independently H or methyl (for example N,N-dimethyl-1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutyl amine hydrochloride optionally in the form of its monohydrate) is used for lowering the uric acid level in humans, for example in humans suffering from or at risk of developing gout, hyperuricaemia or coronary heart disease.