首页> 外国专利> Use of 2-methoxyphenyl-1-methyl-5β-methylethenyl-pyrrole-2-acetamide-acetic acid compound for the production of an anti-inflammatory drug that predicts gastric hyperplasia and renal dysfunction

Use of 2-methoxyphenyl-1-methyl-5β-methylethenyl-pyrrole-2-acetamide-acetic acid compound for the production of an anti-inflammatory drug that predicts gastric hyperplasia and renal dysfunction

机译:2-甲氧基苯基-1-甲基-5β-甲基乙烯基-吡咯-2-乙酰胺-乙酸化合物的生产用于预测胃增生和肾功能不全的抗炎药的使用

摘要

The present invention relates to the use of the compound 2-methoxyphenyl-1-methyl-5p-methylbenzoyl-pyrrol-2-acetamido acetate (known also as amtolmetin guacyl and indicated in the present description also as MED 15) for the production of a NSAID for treating an inflammatory pathological condition with effect of prevention of NSAID-related hydrochloric acid hypersecretion, wherein in order to show its gastro-protective effect same compound has to be administered on empty stomach and without a simultaneous assumption of H1 receptor inhibiting drugs.
机译:本发明涉及化合物2-甲氧基苯基-1-甲基-5p-甲基苯甲酰基-吡咯-2-乙酰氨基乙酸乙酸酯(也称为阿莫美汀番石榴基,在本说明书中也称为MED 15)在制备α-氨基丁酸中的用途。 NSAID用于治疗炎性病理状况,具有预防NSAID相关的盐酸过度分泌的作用,其中为了显示其胃保护作用,必须在空腹中施用相同的化合物,且同时不考虑H1受体抑制药物。

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