18BETA, 19BETA-DIACETILOXI-18ALFA, 19ALFA-EPOXY-3,13 (16), 14-CLERODATRIEN-2-ONA (ESCULENIN A) AND 18BETA, 19BETA-DIACETILOXY-18ALFA, 19ALFA-EPOXY-3,12,14-CLERODATRIEMO (B) A PROCESS FOR PREPARING AND USING THE PRODUCT FOR THE PRODUCTION OF MEDICINES

摘要

The invention relates to the compounds 18 beta , 19 beta -diacetyloxy-18 alpha , 19 alpha -epoxy-3, 13(16), 14-clerodatrien-2-one (Esculentin A) and 18 beta , 19 beta -diacetyloxy-18 alpha , 19 alpha -epoxy-3, 12, 14-clerodatrien-2 beta -isovaleryloxy-6 beta , 7 alpha -diol (Esculentin B) obtained from plants belonging to the Samydaceae family, particularly Casearia esculenta, a process for their preparation, and their use in the manufacture of medicaments. The compounds are particularly useful as anti-inflammatory and/or anti-cancer agents.