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Novel hydroxy and polyhydroxy derivatives of coumarin, preparation thereof and antiviral action thereof
Novel hydroxy and polyhydroxy derivatives of coumarin, preparation thereof and antiviral action thereof
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机译:香豆素的新型羟基和多羟基衍生物,其制备及其抗病毒作用
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摘要
The present invention relates to novel hydroxy and polyhydroxy derivatives of coumarin fused with dialdehydes and aldehyde acids of the general formulae I, II, III and IV: wherein R1 = R2 = 4-hydroxycoumarin; R1 = R2 = 4,7-dihydroxycoumarin; R1 = R2 = 4,5,7-trihydroxycoumarin; R1 = 4-hydroxycoumarin, R2 = -CH(OH)CH3. An object of the invention are also processes for the preparation of hydroxy and polyhydroxy derivatives of coumarin fused with dialdehydes and aldehyde acids, and the antiviral action thereof. Novel hydroxy and polyhydroxy derivatives of coumarin according to the present invention exhibit antiviral action against HIV-1 virus.
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