首页> 外国专利> A process and intermediate compounds for the preparation of 3-ethyl-5-methyl-2-2'-(aminoethoxy)-methyl-4-2''- (chloro)-phenyl-6-methyl-1,4-di-hydro-pyridine-3,5-di- carboxylate benzenesulfonic acid salt benzene sulphonate

A process and intermediate compounds for the preparation of 3-ethyl-5-methyl-2-2'-(aminoethoxy)-methyl-4-2''- (chloro)-phenyl-6-methyl-1,4-di-hydro-pyridine-3,5-di- carboxylate benzenesulfonic acid salt benzene sulphonate

机译:制备3- [乙基] -5- [甲基] -2- [2'-(氨基乙氧基)-甲基] -4- [2''-(氯)-苯基] -6-的方法和中间体化合物[甲基] -1,4-二[氢]吡啶-3,5-二[羧酸盐]苯磺酸盐苯磺酸盐

摘要

A subject matter of the invention is a process for preparing 3-[ethyl]-5-[methyl]-2-[2'-(aminoethoxy)-methyl]-4-[2''- (chloro)-phenyl]-6-[methyl]-1,4-di-[hydro]-pyridine-3,5-di- [carboxylate] benzenesulfonic acid salt of Formula in which 3-[ethyl]-5-[methyl]-2-[2'-(yl)-ethoxy-methyl]-4-[2''-(chloro)- phenyl]-6-[methyl]-1,4-di-[hydro]-pyridine-3,5-di-[carboxylate] hexaminium iodide of Formula is reacted with benzenesulfonic acid of Formula Several variants comprise also reactions for preparing intermediates leading to the said end product. A further subject matter of the invention are intermediates for preparing the said end product.
机译:本发明的主题是制备3- [乙基] -5- [甲基] -2- [2′-(氨基乙氧基)-甲基] -4- [2′-(氯)-苯基]-的方法。下式的6- [甲基] -1,4-二-[氢]吡啶-3,5-二-[羧酸盐]苯磺酸盐其中3- [乙基] -5- [甲基] -2- [2 '-(基)-乙氧基-甲基] -4- [2''-(氯)-苯基] -6- [甲基] -1,4-二-[氢]-吡啶-3,5-二-[使式(I)的[羧酸盐]六碘化with与式(I)的苯磺酸反应。几种变体还包括用于制备产生所述终产物的中间体的反应。本发明的另一主题是用于制备所述终产物的中间体。

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