Use of the cell's own transport system for transferring nucleic acids across the nuclear membrane.

摘要

The invention relates to a nuclear transport agent, to a gene transfer system comprising said nuclear transport agent, to a method of transporting DNA into the nucleus of eukaryotic cells using said nuclear transport agent and to the use of said nuclear transport agent in gene therapy for treating cancer, viral infections, diseases of the nervous system, graft rejection and monogenic or polygenic hereditary diseases.