首页> 外国专利> Use of CD25 binding molecules in the treatment of inflammatory diseases of the gastro-intestinal tract.

Use of CD25 binding molecules in the treatment of inflammatory diseases of the gastro-intestinal tract.

机译:CD25结合分子在胃肠道炎性疾病的治疗中的用途。

摘要

Use of a CD25 binding molecule which comprises at least one antigen binding site comprising at least one domain which comprises in sequence, the hypervariable regions CDR1, CDR2 and CDR3; said CDR1 having the amino acid sequence Arg-Tyr-Trp-Met-His, said CDR2 having the amino acid sequence Ala-Ile-Tyr-Pro-Gly-Asn-Ser-Asp-Thr-Ser-Tyr-Asn-Gln-Lys-Phe-Glu-Gly, and said CDR3 having the amino acid sequence Asp-Tyr-Gly-Tyr-Tyr-Phe-Asp-Phe, in the treatment of inflammatory disease of the gastro-intestinal tract.
机译:包含至少一个抗原结合位点的CD25结合分子的用途,该抗原结合位点包括至少一个结构域,该结构域依次包含高变区CDR1,CDR2和CDR3;所述具有氨基酸序列Arg-Tyr-Trp-Met-His的CDR1,所述具有氨基酸序列Ala-Ile-Tyr-Pro-Gly-Asn-Ser-Asp-Thr-Ser-Tyr-Asn-Gln-的CDR2。 Lys-Phe-Glu-Gly,并且所述CDR3具有氨基酸序列Asp-Tyr-Gly-Tyr-Tyr-Phe-Asp-Phe,用于治疗胃肠道的炎症。

著录项

  • 公开/公告号ZA200207736B

    专利类型

  • 公开/公告日2003-05-08

    原文格式PDF

  • 申请/专利权人 NOVARTIS AG.;

    申请/专利号ZA20020007736

  • 发明设计人 HANSJOERG ADAM;LOTHAR FAERBER;

    申请日2002-09-26

  • 分类号7A61KA;7A61PB;7C07KB;

  • 国家 ZA

  • 入库时间 2022-08-22 00:01:00

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