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USE OF COMPOUNDS BINDING TO A CYTOPLASMATIC DIPEPTIDASE TO POTENTIATE THE IMMUNE RESPONSE
USE OF COMPOUNDS BINDING TO A CYTOPLASMATIC DIPEPTIDASE TO POTENTIATE THE IMMUNE RESPONSE
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机译:与细胞质双肽酶结合的化合物可增强免疫反应
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摘要
A method for stimulating proliferation of T-cells containing cytoplasmic post-prolyl dipeptidase activity; the method, in one aspect, involves contacting the T-cells with an organic compound at a concentration below 10-8M, wherein the compound is characterized in that: (a) it is capable of crossing the membrane of T-cells to enter the cytoplasm, (b) it binds to the dipeptidase activity at a concentration of below 10-8M, and thus (c) stimulates proliferation of the T-cells at that concentration.
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