DIBENZB,F1,4OXAZEPIN-11(10H)-ONES FOR MULTIDRUG RESISTANCE REVERSING AGENTS

摘要

This invention relates to a compound of formula I(see formula I)whereinp is 1 to 3;R1 and R2 each are independently hydrogen or anacyl group R6CO-, in which R6 is C1-6alkyl, C3-7 cycloalkyl, C2-7 alkenyl, aryl orradical of the formula(see formula II)R3 is hydrogen or chloro;R4 and R5 each are independently C1-6 alkyl.Compounds of formula I are useful for thereversal of multidrug resistance of cancer drugs.