HLA MATCHING DONOR-ORIGINATING ACTIVATED LYMPHOCYTES TO BE USED IN PREVENTION/TREATMENT OF TUMORS, INFECTIOUS DISEASES AND AUTOIMMUNE DISEASES, TREATMENT METHOD ACHIEVED BY USING THE LYMPHOCYTES, FORMULA HAVING THE LYMPHOCYTES AS A MAIN CONSTITUENT THEREOF, METHOD FOR MANUFACTURING THE FORMULA AND PREPARATION KIT TO BE USED TO PREPARE THE FORMULA

摘要

HLA matching donor-originating activated lymphocytes highlyeffective in the treatment of patients with tumors, viral infections andautoimmune diseases are prepared by collecting cells contained inperipheral blood originating from an HLA matching donor or peripheralblood originating from an HLA matching donor achieving micro-chimerism and by stimulating and propagating the cells thus collectedwith, for instance, interleukin 2 and anti-CD3 antibodies or the like.The HLA matching donor-originating activated lymphocytes thusprepared can be administered to an HLA matching patient with a tumor,a viral infection or an autoimmune disease for therapeutic or preventivepurposes.