5-AMINOLEVULINIC ACID AND ESTERS, IN COMBINATION WITH ANOTHER PHOTOSENSITIZER, AS PHOTOSENSITIZING AGENTS IN PHOTOCHEMOTHERAPY, AND THEIR USES IN_TREATING WOUNDS

摘要

The method relates to the use of a photosensitizer selected from 5-aminolevulinic acid (5-ALA) and 5-ALA derivatives, and pharmaceuticallyacceptable salts thereof, in the manufacture of a medicament for use intreating a wound. Examples of wounds which may be treated in accordance withthe invention include those resulting from non-physiological processes, e.g.from surgery or from physical injury, abrasions, lacerations, and woundsarising from a thermal injury (e.g. a burn or a wound arising from any cryo-based treatment). Ulcers, e.g. leg ulcers, venous ulcers and gastric ulcers,may also be successfully treated in accordance with the methods of theinvention.