首页> 外国专利> SUSTAINED RELEASE N-TERMINALLY TRUNCATED GALECTIN-3 AND ANTIBODIES TO GALECTIN-3 CARBOHYDRATE LIGANDS FOR USE IN TREATING CANCER

SUSTAINED RELEASE N-TERMINALLY TRUNCATED GALECTIN-3 AND ANTIBODIES TO GALECTIN-3 CARBOHYDRATE LIGANDS FOR USE IN TREATING CANCER

机译:持续释放N末端截短的galectin-3和抗galectin-3碳水化合物的抗体,用于治疗癌症

摘要

There is provided a composition having an effective amount ofN-terminallytruncated galectin-3 in a pharmaceutically acceptable carrier or an effectiveamount of a nucleic acid sequence encoding N-terminally truncated galectin-3in a pharmaceutically acceptable carrier. Also provided by the presentinvention is a method of treating cancer by administering to a patient in needof such treatment an effective amount of N-terminally truncated galectin-3 ina pharmaceutically acceptable carrier or an effective amount of a nucleic acidsequence encoding N-terminally truncated galectin-3 in a pharmaceuticallyacceptable carrier. The present invention also provides an antibody thatspecifically binds to carbohydrate ligands of galectin-3. Further, there isprovided an anti-cancer treatment having an effective amount of N-terminallytruncated galectin-3 and a pharmaceutically acceptable carrier or an effectiveamount of nucleic acid sequence encoding N-terminally truncated galectin-3 ina pharmaceutically acceptable carrier.
机译:提供了具有有效量的N-末端的组合物药学上可接受的载体中的截短的Galectin-3或有效N端截短的galectin-3的核酸序列的数量在药学上可接受的载体中。目前还提供本发明是一种通过向有需要的患者给药来治疗癌症的方法。这种治疗的有效量的N-末端截短的galectin-3药学上可接受的载体或有效量的核酸药学上编码N端截短的Galectin-3的序列可接受的载体。本发明还提供了一种抗体,其与半乳凝素3的碳水化合物配体结合。此外,还有提供了具有有效量的N末端的抗癌治疗截短的galectin-3和药学上可接受的载体或有效药物编码N末端截短的galectin-3的核酸序列的数量药学上可接受的载体。

著录项

  • 公开/公告号CA2488850A1

    专利类型

  • 公开/公告日2002-12-19

    原文格式PDF

  • 申请/专利权人 MANDALMED INC.;

    申请/专利号CA20022488850

  • 申请日2002-06-10

  • 分类号C12N15/12;A61K48/00;A61K38/17;C07K16/28;A61K39/395;A61K31/7088;

  • 国家 CA

  • 入库时间 2022-08-21 23:57:55

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