Magnetic nanoparticles for bioseparation application and methods for producing same

摘要

This invention relates to the controlled crystallization of magnetite to form superparamagnetic nanoparticles. The particles are highly crystalline magnetite in the 10 to 250 nm, 10 to 200, 20-200 and preferably 50 to 150 nm diameter range, exhibiting superparamagnetic characteristics with a saturation magnetization of 62 emu/g. The particles are stabilized with a coating such as dextran. These particles have potential applications in biological cell separations, drug delivery and nondestructive clinical diagnosis.