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Usp-3like deubiquitinating enzyme gene disruptions, compositions and methods related thereto
Usp-3like deubiquitinating enzyme gene disruptions, compositions and methods related thereto
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机译:Usp-3样去泛素化酶基因的破坏,组成及其相关方法
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摘要
The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a USP3-like deubiquitinating enzyme gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene functions, and as potential treatments for various disease states and disease conditions.
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