Calcitonin-like sequence expressed by gonadotropes of the anterior pituitary

摘要

A cDNA sequence has been identified for an anterior pituitary-derived peptide (pit-CT) produced and secreted by the pituitary cells. The pit-CT has substantial sequence homology to calcitonin (CT) and has biological properties similar to salmon calcitonin (SCT). The pit-CT may be used to treat various diseases, such as osteoporosis, Paget s, and Prolactinoma.