Factors for angiogenesis, vasculogenesis, cartilage formation, bone formation and methods of use thereof

摘要

The application is related to the field of nucleic acids with identifed utility, and more particularly, to genes, related nucleic acids, their complements, polypeptides, and methods of using hte same for blood vessel, cartilage, and bone formation, as well as inhibition thereof. The application describes discoveries made using the zebrafish embryo technique, as well as other techniques that are described herein. The discoveries include genes, related nucleic acids, and their complements as, well as sequences, polypeptides, other molecules, and methods for using them, e.g., TDE1, PTV, MOESIN, and HKE4. Also described are polypeptide products, inhibition of expression, administration of materials and products, screening procedures, and techniques for making drugs. Moreover, uses of these discoveries in appropriate contexts are set forth.