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Tissue inhibitor of matrix metalloproteinases type-1 (timp-1) as a postoperative marker for minimal residual disease or recurrent disease in patients with a prior history of cancer
Tissue inhibitor of matrix metalloproteinases type-1 (timp-1) as a postoperative marker for minimal residual disease or recurrent disease in patients with a prior history of cancer
The present invention describes a method for determining whether an individual is suffering from minimal residual diseases or recurrent cancer during treatment and/or after being treated for the primary cancer by determining a parameter representing the post-operative TIMP-1 concentration in body fluid samples from the individual. In addition, the invention describes the additive effect of combined post-operative measurements of plasma TIMP-1 and serum CEA.
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