Compositions and methods for promoting weight loss, thermogenesis, appetite suppression, lean muscle mass, increasing metabolism and boosting energy levels, and use as a dietary supplement in mammals

摘要

The invention is both a composition and a method for promoting weight loss in mammals, for promoting thermogenesis in mammals, for increasing metabolism and boosting energy levels in mammals, promoting appetite suppression in mammals, for promoting lean muscle mass in mammals and for a diet supplement. The primary mechanism of action for the invention is that it increases norepinephrine levels, which promotes a rise in metabolism, thus leading to more calories burned and more energy expended primarily through the burning or metabolism of adipose tissue (fat) through lipolysis, without the destruction or metabolism of muscle tissue. The present invention relates to a nutritional supplement composition, and the methods for the administration thereof, comprising of (1) an effective amount of epigallocatechin gallate (EGCG), the chemical name of which has been described as ((2R,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1[2H]-benzopyran-3,5,7-triol 3-(3,4,5-trihydroxybenzoate), and (2) various other substances (singly or in any combination thereof), which either (a) inhibit cyclic adenosine monophosphate (cAMP) phosphodiesterase, (b) stimulate lipolysis, (c) stimulate thermogenesis (i.e., increase metabolism) (d) and/or increase norepinephrine levels, or (e) any combination thereof. In a preferred embodiment, the basic invention is a composition, and a method for the administration thereof, comprising effective amounts of epigallocatechin gallate, caffeine, and l-tyrosine.