首页> 外国专利> Methods to identify anti-tumoral agents inhibiting rasgap / aurora kinase interactions

Methods to identify anti-tumoral agents inhibiting rasgap / aurora kinase interactions

机译:鉴定抑制rasgap / Aurora激酶相互作用的抗肿瘤药物的方法

摘要

METHODS TO IDENTIFY ANTI-TUMORAL AGENTS INHIBITING RasGAP / AURORA KINASE INTERACTIONS The present invention concerns new methods for for identifying a biologically active compound with antitumoral properties wherein said compound is studied for its capacity to inhibit the interaction- between RasGAP and the Drosophila melanogaster Aurora kinase or an ortholog of said kinase, or a fragment thereof able to interact with RasGAP,- or between RasGAP, an Aurora-binding protein and the Drosophila melanogaster Aurora kinase or an ortholog of said kinase, or a fragment thereof able to interact with RasGAP.
机译:鉴定抑制RasGAP / Aurora激酶相互作用的抗肿瘤剂的方法本发明涉及用于鉴定具有抗肿瘤特性的生物活性化合物的新方法,其中研究了所述化合物抑制RasGAP与Drosophila melanogaster Aurora激酶之间相互作用的能力。或所述激酶的直系同源物,或其能够与RasGAP相互作用的片段,或在RasGAP,极光结合蛋白和果蝇果蝇Aurora激酶之间,或所述激酶的直系同源物,或其片段,能够与RasGAP相互作用。

著录项

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号