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METHOD FOR THE DETERMINATION OF AT LEAST ONE FUNCTIONAL POLYMORPHISM IN THE NUCLEOTIDE SEQUENCE OF A PRESELECTED CANDIDATE GENE AND ITS APPLICATIONS
METHOD FOR THE DETERMINATION OF AT LEAST ONE FUNCTIONAL POLYMORPHISM IN THE NUCLEOTIDE SEQUENCE OF A PRESELECTED CANDIDATE GENE AND ITS APPLICATIONS
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机译:候选候选位点基因核苷酸序列中至少一个功能多态性的测定方法及其应用
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摘要
The present invention concerns a method for determining at least one functional SNP in a gene, comprising preselecting a candidate gene, providing a sample population comprising a significant number of individuals chosen substantially at random from the general population, isolating from each individual of the sample population at least one fragment of the nucleotide sequence of the preselected candidate gene, identifying at least one SNP in at least one fragment and determining the functionality of said SNP(s). The present invention also concerns applications of this method.
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