首页> 外国专利> METHOD FOR ANALYZING CELLULAR EVENTS IN A SAMPLE BY MEASURING TRANSMITTED AND/OR REFLECTED ELECTROMAGNETIC TEST SIGNALS IN A FREQUENCY RANGE FROM 500 KHZ TO 1000 GHZ

METHOD FOR ANALYZING CELLULAR EVENTS IN A SAMPLE BY MEASURING TRANSMITTED AND/OR REFLECTED ELECTROMAGNETIC TEST SIGNALS IN A FREQUENCY RANGE FROM 500 KHZ TO 1000 GHZ

机译:通过测量500 KHZ至1000 GHZ频率范围内透射和/或反射的电磁测试信号来分析样品中的细胞事件的方法

摘要

The invention makes it possible to detect cellular activity without knowing specifically what activity is being detected, although detection of specific activity is possible. The assay comprises coupling an electromagnetic test signal in the specified frequency range to a sample in which a cellular event is being detected, whereby the sample interacts with and modulates the test signal to produce a modulated test signal; detecting the modulated test signal; and analyzing the modulated test signal to detect said cellular event. The invention is useful in the detection of cellular activity induced by the presence of a test substance in the medium in which a cell is located and provides advantages for lead optimization in the drug discovery field.
机译:尽管可以检测比活性,但是本发明使得可以在不特别知道检测到什么活性的情况下检测细胞活性。该测定包括将指定频率范围内的电磁测试信号耦合到正在检测到细胞事件的样品,从而该样品与测试信号相互作用并对其进行调制以产生调制的测试信号。检测调制后的测试信号;分析经调制的测试信号以检测所述蜂窝事件。本发明可用于检测由细胞所在的培养基中受试物质的存在引起的细胞活性,并为药物发现领域中的前导优化提供优势。

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