BUCCAL, NON-POLAR SPRAY FOR NITROGLYCERIN

摘要

A buccal aerosol spray using a non-polar solvent has now been developed which provides nitroglycerin for rapid absorption through the oral mucosa, resulting in fast onset of effect. The buccal aerosol spray of the invention comprises: propellant 50-95 %, non-polar solvent 5-50 %, nitroglycerin 0.001-15 %, flavoring agent 0.05-5 %.