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Mechanism oriented inhibitors of dipeptidyl peptidase I
Mechanism oriented inhibitors of dipeptidyl peptidase I
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机译:机制化的二肽基肽酶I抑制剂
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摘要
N-Dipeptidyl O-acyl hydroxylamine derivatives (I) are new. Compounds of formula (I) are new: A-B-NH-O-Q (I). A = any N-terminally unprotected amino acid other than proline and hydroxyproline; B = any amino acid other than proline, hydroxyproline and alanine; Q = acyl, preferably benzoyl optionally substituted by F, Cl, Br, NH2, Me and/or OMe
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机译:N-二肽基O-酰基羟胺衍生物(I)是新的。式(I)的化合物是新的:A-B-NH-O-Q(I)。 A =脯氨酸和羟脯氨酸以外的任何N端未保护的氨基酸; B =脯氨酸,羟脯氨酸和丙氨酸以外的任何氨基酸; Q =酰基,优选被F,Cl,Br,NH 2,Me和/或OMe取代的苯甲酰基
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