GENES OVEREXPRESSES BY OVARIAN CANCER AND THEIR USE IN DEVELOPING NOVEL THERAPEUTICS ESPECIALLY ANTIBODIES

摘要

Nucleic acid sequences encoding genes that are overexpressed by human ovarian cancers are provided. These genes and the corresponding antigens are useful diagnostic and therapeutic targets. The invention provides cancer therapies that target these antigens, especially using monoclonal antibodies that target the Anat-2 antigen.