首页> 外国专利> A PROCESS FOR PRODUCING A FRACTION ENRICHED UPTO 100 OF 3-O-ACETYL-11-KETO-β-BOSWELLIC ACID FROM AN EXTRACT CONTAINING A MIXTURE OF BOSWELLIC ACIDS

A PROCESS FOR PRODUCING A FRACTION ENRICHED UPTO 100 OF 3-O-ACETYL-11-KETO-β-BOSWELLIC ACID FROM AN EXTRACT CONTAINING A MIXTURE OF BOSWELLIC ACIDS

机译:一种从含有混合乳香酸的提取物中制备浓缩至多100%的3-O-乙酰基-11-酮-β-乳香酸的方法

摘要

The invention relates to a process for producing a fraction enriched upto 100 % of 3-O-acetyl-11-keto-β-boswellic acid. An organic solvent extract of gum resin from Boswellia species is first subjected to oxidation and then acetylation or vice versa. This converts the less potent boswellic acids present in the fraction to AKBA. This treated fraction is subjected to further purification and separation by chromatographic separation techniques to enhance its purity and to remove contaminants therefrom. This process provide an access to a fraction enriched in 10 -100 % AKBA for therapeutic applications.
机译:本发明涉及一种生产浓缩至多100%的3-O-乙酰基-11-酮-β-乳香酸的馏分的方法。首先对来自乳香物种的树胶树脂的有机溶剂提取物进行氧化,然后进行乙酰化,反之亦然。这会将馏分中存在的效力较低的乳香酸转化为AKBA。通过色谱分离技术对该处理的级分进行进一步的纯化和分离,以提高其纯度并从中除去污染物。该方法为治疗应用提供了富含10 -100%AKBA的馏分的途径。

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