首页> 外国专利> HUMAN LEUCINE-RICH REPEAT FAMILY MEMBER AND USES THEREOF

HUMAN LEUCINE-RICH REPEAT FAMILY MEMBER AND USES THEREOF

机译:富含人亮氨酸的重复家族成员及其用途

摘要

The invention provides isolated nucleic acids molecules, designated 31939 nucleic acid molecules, which encode novel leucine-rich repeat (LRR) members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 31939 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 31939 gene has been introduced or disrupted. The invention still further provides isolated 31939 proteins, fusion proteins, antigenic peptides and anti-31939 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
机译:本发明提供了分离的核酸分子,称为31939核酸分子,其编码新的富亮氨酸重复序列(LRR)成员。本发明还提供了反义核酸分子,含有31939个核酸分子的重组表达载体,已将表达载体引入其中的宿主细胞,以及已引入或破坏了31939基因的非人类转基因动物。本发明还提供了分离的31939蛋白,融合蛋白,抗原肽和抗31939抗体。还提供了利用本发明的组合物的诊断方法。

著录项

  • 公开/公告号EP1268789A2

    专利类型

  • 公开/公告日2003-01-02

    原文格式PDF

  • 申请/专利权人 MILLENNIUM PHARMACEUTICALS INC.;

    申请/专利号EP20010922939

  • 发明设计人 GLUCKSMANN MARIA ALEXANDRIA;

    申请日2001-03-30

  • 分类号C12N15/12;C07K14/47;C12N15/63;C12N5/10;C07K16/18;C12P21/00;G01N33/53;C12Q1/68;

  • 国家 EP

  • 入库时间 2022-08-21 23:50:59

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