USE OF 3'-UTR'S FROM CYSTEINE PROTEINASE GENES CPB2 AND CPB2.8 OF LEISHMANIA FOR DIRECTING STAGE-SPECIFIC EXPRESSION

摘要

The present invention relates to the identification and use of sequence elements present in the intergenic region of Cysteine Proteinase Genes, cpb, in L. mexicana and the observation that the identified sequences are involved in the control of stage-regulated gene expression. Principal uses include the preparation of vaccines.