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Microarray data warehouse

机译:芯片数据仓库

摘要

The data-warehouse disclosed in this application focuses on providing both structure and algorithms suitable for statistical analysis of a microarray database's entire contents including the experiment annotations. It addresses the rapid growth of the amount of hybridisation data obtained from microarrays, more detailed experimental descriptions, and new kinds of experiments in the future. A storage concept is disclosed and in one embodiment it is applied to an organism-specific database. Although the databases may contain different ontologies of experiment annotations, they share the same structure and therefore can be accessed by the very same statistical algorithms. Experiment ontologies have not yet reached their final shape, and standards are reduced to minimal conventions that do, not yet warrant extensive description. An ontology-independent structure enables updates of annotation hierarchies during normal database operation without altering the structure.
机译:在本申请中公开的数据仓库着重于提供适合于对包括实验注释的微阵列数据库的全部内容进行统计分析的结构和算法。它解决了从微阵列获得的杂交数据数量的快速增长,更详细的实验描述以及未来的新型实验。公开了一种存储概念,并且在一个实施例中,将其应用于生物体特异性数据库。尽管数据库可能包含不同的实验注释本体,但是它们共享相同的结构,因此可以通过完全相同的统计算法进行访问。实验本体还没有达到最终的形状,并且标准被简化为可以做到的最低限度的惯例,因此尚无广泛的描述。独立于本体的结构可在正常数据库操作期间更新注释层次结构,而无需更改结构。

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