Sulfonamide derivatives of 3-substituted imidazo1,2-D-1,2,4-thiadiazoles and 3-substituted-1,2,4thiadiazolo4,5-Abenzimidazole as inhibitors of fibrin cross-linking and transglutaminases

摘要

A method of inhibiting the activity of transglutaminases containing a cysteine residue comprising administering to a mammal an effective amount of a sulfonamide derivative of imidazo[1,2-d]-1,2,4-thiadiazoles sufficient to inhibit the activity.