5.5 TRIAZASPIRO5.5UNDECANE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT

摘要

The present invention is triaza-spiro represented by the general formula (I) [5. 5] undecane derivatives, quaternary ammonium salts thereof, and their N- oxides, their nontoxic salt, or a pharmaceutical agent containing it as an active ingredient and an object thereof is to provide a (symbols in the formula are the same as described according to the specification) .; Formula I ; The compound represented by the above formula (I) for preventing and / such as due to control the action of chemokine / chemokine receptor, various inflammatory diseases, asthma, atopic dermatitis, urticaria, allergic diseases, nephritis, nephritis, hepatitis, arthritis, chronic articular rheumatism or useful in the treatment.