APP C pCT105 Development of alzhemier-inducible cell line by Tet-On with recombinant pCT105 vector in APP

摘要

PURPOSE: Provided is development of alzheimer-inducible cell line by Tet-On with recombinant pCT105 vector in APP. The developed alzheimer-inducible cell line is useful for development of therapeutics of multi-infarct dementia, Alzheimer disease, Parkinson disease, hypothyroidism, etc. CONSTITUTION: A development system contains a recombinant pCT 105 vector selected from Tet-on CT105 as a main system, and if required at least one of vector separated by the solvent selected from water, albumin, an auxiliary agent and a stabilizing agent.