Bonding method to induce functional group for ion exchange

摘要

PURPOSE: Provided is a method for producing anion exchange column or cation exchange column by directly introducing a suitable silane compound having anionic or cationic functional group into commercially available various purified silica. CONSTITUTION: The method comprises directly bonding at least one silane compound selected from the group consisting of N-trimethoxypropyl-N,N,N-trimethylammonium chloride, N-(trimethoxysilyl ethyl)benzyl-N,N,N-trimethylammonium chloride, octadecyldimethyl(3-trimethoxysilyl propyl)ammonium chloride, and N,N-didecyl-N-methyl-N-methyl-N-(3-trimethoxysilyl propyl)ammonium chloride which have anion exchange functional group, to a purified silica gel, so as to form a filler for anion chromatography.