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METHOD AND SYSTEM FOR EXPECTING INTERACTION BETWEEN PROTEINS BY USING DOMAIN COMBINATION INFORMATION

机译:利用域组合信息预测蛋白质间相互作用的方法和系统

摘要

The method and system of a possibility that the present invention relates to for statistically predicting the interaction between two kinds of protein, especially protein between group protein interaction and without interacting protein to difference structure domain combination (domain combination between group and group) based on the information from its angle analysis come forecast image protein to a possibility that. Interaction. ;Predict interaction between protein of the invention for this purpose, probability of occurrence information of the interacting protein to group and non-interaction protein to each selection for extracting specific domain combination from the corresponding group of group, and storing step and storage domain, it determines the chance with the expression interaction of any two protein using combined probability of happening information, and it is characterized in that it includes the steps that obtaining any one of two protein with probability det interactions. From probability equation. ;When in the present invention, with a possibility that interaction by prediction utilize the single domain using domain combined information to the traditional prediction method and system of (single domain to) compared with, it is expected that significantly improved predictive ability. Between protein and improvement.
机译:本发明涉及一种方法和系统,其用于基于统计学方法预测两种蛋白质之间的相互作用,特别是组蛋白质相互作用之间的蛋白质之间的相互作用以及不与差异结构域组合(组与组之间的域组合)相互作用的蛋白质。从其角度分析信息可以预测图像蛋白的可能性。相互作用。 ;为此目的,预测本发明蛋白质之间的相互作用,相互作用蛋白质与基团和非相互作用蛋白质的发生信息的概率,以从各组对应的组中提取特定的域组合,并存储步骤和存储域,利用发生信息的组合概率确定任意两种蛋白质表达相互作用的机会,其特征在于它包括获得概率det相互作用的两种蛋白质中任何一种的步骤。从概率方程式。当在本发明中,与传统的预测方法和系统(单域到)相比,通过预测的交互有可能利用使用域组合信息的单域进行预测时,可以显着提高预测能力。在蛋白质和改善之间。

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