METHOD FOR TREATING LOCALLY GENERALIZED STOMACH CANCER BY APPLYING COMBINED THERAPY

摘要

FIELD: medicine. SUBSTANCE: method involves administering two systemic polychemotherapy courses with 3 weeks long pause between the courses. The following treatment schedule is suggested. Metotrexate is intravenously administered at a dose of 5mg/m² as bolus dose from the first to the fifth day. Carboplatin is administered at a dose of 50mg/m² as 45 min long intravenous infusion from the first to the fifth day. 5-fluorouracyl is administered at a dose of as 3 h long intravenous infusion from the first to the fifth day. Surgical intervention is carried out 3 weeks later, after the polychemotherapy course being over. Cisplatin is administered at a dose of 15mg/m² during the operation. EFFECT: enhanced effectiveness in treating III stage stomach cancer cases.