PURIFIED ANTIGENIC POLYPEPTIDE WITH PROTECTION PROPERTY AGAINST INFECTION ECHINOCOCCUS GRANULOSIS, DNA MOLECULE ENCODING INDICATED ANTIGENIC POLYPEPTIDE, PREPARATION COMPRISING INDICATED ANTIGENIC POLYPEPTIDE, VACCINE COMPRISING INDICATED ANTIGENIC POLYPEPTIDE OR INDICATED DNA MOLECULE

摘要

FIELD: genetic engineering, immunology, molecular biology, veterinary science. SUBSTANCE: invention describes novel antigenic polypeptide, its fragments and variants able to produce protective immune response in body infection with Echinococcus granulosis. Invention reports nucleotide sequence encoding indicated forms of antigenic polypeptide being insertion of these sequences into corresponding vector systems provides the possibility for preparing novel antigens by method of recombinant DNAs. Invention relates also to development, along with vaccines comprising ready antigenic polypeptide, recombinant viral vaccines including nucleic acid with its expression in the animal body. Proposed vaccines are designated for protection of hosts susceptible to infection with parasites of genus Echinococcus. EFFECT: valuable properties of polypeptide, vaccine. 7 cl, 4 dwg, 5 tbl, 7 ex