METHOD PREDICTING CLINICAL COURSE OF UVEA MELANOMA BASED ON APOPTHOSIS MARKER p53

摘要

FIELD: medicine, ophthalmology, in particular. SUBSTANCE: method is realized by means of immunohistochemical analysis of cells of removed tumor, percentage of cells expressing p53 with relation to total number of tumor cells in field of vision is established. If their number exceeds 20% and more probability of progressing metastasis is predicted in 65% of cases. EFFECT: increased accuracy and objectivity of prediction of clinical course of uvea melanoma. 3 dwg