RECEPTORS-MEDIATED DELIVERY OF GENES BY USING VECTORS BASED UPON BACTERIOPHAGES

摘要

FIELD: medicinal genetics. SUBSTANCE: the present innovation deals with filamentous phage particles with ligands on their surface. These particles are used to deliver therapeutic gene to cells. Ligand is the protein developed at fusion to phage capsid protein covalently conjugated with phage particles. EFFECT: increased number of gene therapeutic preparations. 45 cl, 9 dwg, 9 ex, 1 tbl