A method for measuring the effect of substances on the regulatory cells or cell envelopes excitability

摘要

The present invention relates to a method for measuring the effect of a substance to a neural cell unit, whereby in a first step of the cell cluster is brought into a solution, and in a second process step, the bioelectric activity of the cell association is measured, in a third step via the change in at least one ion concentration of the enveloping solution defined activity states of the neural dressing be adjusted, and in a fourth method step of the material of the solution to be tested is added, during and / or after the addition of the substance the activity of the cell association and their change to the output value is measured. On the basis of the change in the bioelectric activity is on the mode of operation of the substance the conclusion of the rear of the.