Preparation of optionally functionalized enantio-pure/enriched amines useful as intermediates for e.g. pharmaceuticals by reductive hydridotransfer amination of carbonyl compounds comprises use of Group VIII metal complex catalyst

摘要

Preparation of amines by reductive hydridotransfer-amination of aldehydes or ketones with ammonia or primary or secondary amines in presence of a hydrogen-donor as reductant with catalysis being by a transition metal complex containing iron, ruthenium, osmium, cobalt, rhodium, iridium, nickel, palladium or platinum.