New hydrolysis-stable complexes of beta-diketone, metal and antitumor agent such as melaphalan or tegafur, useful as broad-spectrum antitumor agents

摘要

New complexes (I) comprise a beta -diketone, a metal and a compound having at least one group containing nitrogen, oxygen or sulfur. Complexes of formula D2-M-T (I), where M and T show electron donor-acceptor interaction and M in the complex has a free coordination site, are new. D = beta -diketone; M = metal atom selected from chromium, copper, manganese, iron, nickel, copper, zinc and molybdenum; and T = compound having at least one group containing nitrogen, oxygen or sulfur.